Novel culture media enhances mononuclear cells from patients with chronic limb-threatening ischemia to increase vasculogenesis and anti-inflammatory effect.
Nuttapol ChruewkamlowKanin PruekprasertPhakawan PhutthakunphithakOnchira AcharayothinTossapol PrapassaroKiattisak HongkuSuteekhanit HahtapornsawanNattawut PuangpunngamKhamin ChinsakchaiChumpol WongwanitChanean RuangsetakitNuttawut SermsathanasawadiPublished in: Stem cell research & therapy (2021)
MNCs from CLTI patients that were cultured in QQ culture media had a significantly higher number of CD34+CD133+ cells and anti-inflammatory cells, and higher angiogenesis-related function compared to MNCs cultured in standard culture media.
Keyphrases
- anti inflammatory
- induced apoptosis
- endothelial cells
- cell cycle arrest
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- endoplasmic reticulum stress
- prognostic factors
- signaling pathway
- peritoneal dialysis
- oxidative stress
- cell death
- vascular endothelial growth factor
- cell proliferation
- patient reported