Rapid Expansion of Human Epithelial Stem Cells Suitable for Airway Tissue Engineering.
Colin R ButlerRobert Edward HyndsKate H C GowersDani Do Hyang LeeJames M BrownClaire CrowleyVitor H TeixeiraClaire M SmithLuca UrbaniNicholas J HamiltonRicky M ThakrarHelen L BoothMartin A BirchallPaolo De CoppiAdam GiangrecoChristopher O'CallaghanSamuel M JanesPublished in: American journal of respiratory and critical care medicine (2017)
Our method generates large numbers of functional airway basal epithelial cells with the efficiency demanded by clinical transplantation, suggesting its suitability for use in tracheal reconstruction.