Extracellular Matrix Determines Biomechanical Properties of Chondrospheres during Their Maturation In Vitro.
Nikolai P OmelyanenkoPavel A KaralkinElena A BulanovaElizaveta V KoudanVladislav A ParfenovSergei A RodionovAlisa D KnyazevaVladimir A KasyanovIgor I BabichenkoTamara Z ChkaduaYusef D KhesuaniAnna A GryadunovaVladimir A MironovPublished in: Cartilage (2018)
Extracellular matrix is one of the main structural determinants of chondrospheres biomechanical properties during chondrogenic maturation in vitro. The estimation of tissue spheroids' physical behavior in vitro prior to operative treatment can be used to predict and potentially control fusogenic self-assembly process after implantation in vivo.