Tracking of Tumor Cell-Derived Extracellular Vesicles In Vivo Reveals a Specific Distribution Pattern with Consecutive Biological Effects on Target Sites of Metastasis.
Mirjam GerwingVanessa KocmanMiriam StöltingAnne HelfenMax MasthoffJohannes RothKatarzyna Barczyk-KahlertLilo GreuneM Alexander SchmidtWalter HeindelCornelius FaberSimone KönigMoritz WildgruberMichel EisenblätterPublished in: Molecular imaging and biology (2020)
In conclusion, distribution of tumor cell-derived extracellular vesicles follows a specific pattern and can be monitored, using dedicated imaging. Extracellular vesicles alter the immune cell composition in target organs of metastasis, using a specific proteome cargo.
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