Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis.

Yaqian QuRuonan ZhaiDandan WangZheng WangGuangjie HouChenchen WuMeian TangXiongbin XiaoJie JiaoYue BaFang ZhouJian QiuWu Yao

Published in: Journal of translational medicine (2023)

Our study suggests that mitochondrial folate pathway regulates myofibroblast differentiation and could serve as a potential target for ameliorating silica-induced pulmonary fibrosis.

Keyphrases

pulmonary fibrosis
high glucose
oxidative stress
diabetic rats
drug induced
endothelial cells
risk assessment
signaling pathway