CSF-Derived CD4+ T-Cell Diversity Is Reduced in Patients With Alzheimer Clinical Syndrome.
Chaitanya JoshiKarthigayini SivaprakasamScott ChristleySara IrelandJacqueline RivasWei ZhangDanielle SaderRebecca LoganDoris Lambracht-WashingtonRoger RosenbergMunro CullumBrian HittQuan-Zhen LiRobert BarberBenjamin GreenbergLindsay CowellRong ZhangAnn StoweRyan HuebingerBrendan KelleyNancy MonsonPublished in: Neurology(R) neuroimmunology & neuroinflammation (2021)
Examination of CSF indicates that CD4+ T cell-mediated adaptive immune responses are altered in patients with ACS. Understanding the underlying mechanisms affecting adaptive immunity will help move us toward the goal of slowing cognitive decline.