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Statin-Induced Necrotizing Autoimmune Myopathy: Case Report of a Patient under Chronic Treatment.

Ilaria Anna BellofattoMarta SessaregoAmedeo TirandiChiara OliveroCosimo SguraElia MaioliAurora GavociElisa SchiavettaFederica FrèBenedetta SaccomannoFederico ZaottiniRiccardo PicassoChiara FiorilloLuca LiberaleLuciano Carlo OttonelloNicholas BardiFabrizio Montecucco
Published in: Case reports in medicine (2023)
Recognizing SINAM is paramount in order to promptly start treatment and avoid permanent muscle damage. Using a combination therapy from the beginning could contribute to a better outcome. Prompt statin cessation, categorization of the muscle disease by autoantibody testing, imaging, and histology, exclusion of malignancy, and anti-inflammatory therapy with corticosteroids, antimetabolites, immunoglobulins, and in some cases rituximab are currently accepted approaches to this entity.
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