Impact of Human Immunodeficiency Virus Drug Resistance Mutations Detected in Women Prior to Antiretroviral Therapy With Efavirenz + Tenofovir Disoproxil Fumarate + Lamivudine (or Emtricitabine).
Ceejay L BoyceTatiana SilsRoss S MilneJackson J WallnerSamantha R HardyDaisy KoAnnie Wong-On-WingMalia MackeyNikki HigaIngrid A BeckSheila M StyrchakPatricia DeMarraisCamlin TierneyMary G FowlerLisa M Frenkelnull nullPublished in: Open forum infectious diseases (2024)
Resistance to NNRTI alone was prevalent and dual-class (NRTI and NNRTI) resistance was rare in this cohort, with only the latter associated with virologic failure. This confirms others' findings that, if needed, efavirenz-based ART offers most people an effective alternative to dolutegravir-based ART.