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Blood purification could tackle COVID-19?

Hiroyuki YamadaShigeru Ohtsuru
Published in: Journal of intensive care (2021)
Coronavirus disease 2019 (COVID-19) threatened human lives worldwide since first reported. The current challenge for global intensivists is to establish an effective treatment for severe COVID-19. Blood purification has been applied to the treatment of various critical illnesses. Theoretically, its technique also has an enormous possibility of treating severe COVID-19 in managing inflammatory cytokines and coagulopathy. Recent clinical studies have revealed the positive clinical effect of therapeutic plasma exchange. Other studies have also indicated the considerable potential of other blood purification techniques, such as Cytosorb, AN69 surface-treated membrane, and polymyxin b hemoperfusion. Further research is needed to elucidate the actual effects of these applications.
Keyphrases
  • coronavirus disease
  • sars cov
  • respiratory syndrome coronavirus
  • endothelial cells
  • combination therapy
  • single cell
  • recombinant human
  • multidrug resistant
  • induced pluripotent stem cells