Antithrombotic Therapy and Cardiovascular Outcomes After Transcatheter Aortic Valve Implantation in Patients Without Indications for Chronic Oral Anticoagulation: A systematic review and network meta-analysis of randomized controlled trials.
Paul GuedeneyVincent RouleJules MesnierCeline ChapelleJean-Jacques PortalSylvie LaporteEdouard OllierMichel ZeitouniMathieu KerneisNiki ProcopiOlivier BarthelemySabato SorrentinoMichal MihalovicJohanne SilvainEric VicautGilles MontalescotJean Philippe ColletPublished in: European heart journal. Cardiovascular pharmacotherapy (2023)
Following TAVI in patients without an indication for chronic oral anticoagulant, SAPT more than halved the risk of bleeding compared to DAPT and direct oral anticoagulant-based regimens without significant ischemic offset.
Keyphrases
- transcatheter aortic valve implantation
- atrial fibrillation
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- venous thromboembolism
- aortic stenosis
- aortic valve
- prognostic factors
- aortic valve replacement
- peritoneal dialysis
- stem cells
- oxidative stress
- mesenchymal stem cells
- patient reported outcomes
- acute coronary syndrome
- cell therapy