Antithrombotic Therapy and Cardiovascular Outcomes After Transcatheter Aortic Valve Implantation in Patients Without Indications for Chronic Oral Anticoagulation: A systematic review and network meta-analysis of randomized controlled trials.

Paul GuedeneyVincent RouleJules MesnierCeline ChapelleJean-Jacques PortalSylvie LaporteEdouard OllierMichel ZeitouniMathieu Kerneis Niki Procopi Olivier BarthelemySabato SorrentinoMichal MihalovicJohanne SilvainEric VicautGilles Montalescot Jean Philippe Collet

Published in: European heart journal. Cardiovascular pharmacotherapy (2023)

Following TAVI in patients without an indication for chronic oral anticoagulant, SAPT more than halved the risk of bleeding compared to DAPT and direct oral anticoagulant-based regimens without significant ischemic offset.

Keyphrases

transcatheter aortic valve implantation
atrial fibrillation
end stage renal disease
ejection fraction
newly diagnosed

chronic kidney disease
venous thromboembolism
aortic stenosis
aortic valve
prognostic factors

aortic valve replacement
peritoneal dialysis
stem cells
oxidative stress

mesenchymal stem cells
patient reported outcomes
acute coronary syndrome
cell therapy