Neurotrophic interactions between neurons and astrocytes following AAV1-Rheb(S16H) transduction in the hippocampus in vivo.
Min-Tae JeonGyeong Joon MoonSehwan KimMinji ChoiYong-Seok OhDong Woon KimHyung-Jun KimKea Joo LeeYoungshik ChoeChang Man HaIl-Sung JangMichiko NakamuraCatriona McLeanWon-Suk ChungWon-Ho ShinSeok-Geun LeeSang Ryong KimPublished in: British journal of pharmacology (2019)
The results demonstrated that Rheb(S16H) transduction of hippocampal neurons could strengthen the neuroprotective system and this intensified system may have a therapeutic value against neurodegeneration in the adult brain.