Histone methyltransferase Smyd2 contributes to blood-brain barrier breakdown in stroke.

Jinghuan WangWen ZhongQianwen ChengChenxi XiaoJie XuZhenghua SuHaibi SuXinhua Liu

Published in: Clinical and translational medicine (2022)

Overall, these results reveal a novel role for Smyd2 in BBB disruption in ischaemic stroke, suggesting that Smyd2 may represent a new therapeutic target for ischaemic stroke.

Keyphrases

blood brain barrier
cerebral ischemia
atrial fibrillation
dna methylation
genome wide
gene expression