Rapid Whole Genome Characterization of High-Risk Pathogens Using Long-Read Sequencing to Identify Potential Healthcare Transmission.

Chin-Ting WuWilliam C ShropshireMicah M BhattiSherry CantuIsrael K GloverSelvalakshmi Selvaraj AnandXiaojun LiuAwdhesh KaliaTodd J TreangenRoy F ChemalyAmy SpalloneSamuel Shelburne

Published in: medRxiv : the preprint server for health sciences (2024)

Via a stand-alone ONT pipeline, we detected potentially transmitted HAI pathogens rapidly and accurately, aligning closely with epidemiological data. Our low-resource method has the potential to assist in the efficient detection and deployment of preventative measures against HAI transmission.

Keyphrases

healthcare
loop mediated isothermal amplification
gram negative
human health
single cell
single molecule
risk assessment
machine learning
climate change
label free
health insurance