The association of pain impact and sleep disruption with opioid withdrawal during opioid-use disorder treatment.

Jennifer D EllisDaniel HanJami MayoJ Gregory HobelmannPatrick H FinanAndrew S Huhn

Published in: British journal of clinical pharmacology (2024)

Pain impact and sleep disturbance are 2 factors associated with opioid withdrawal and opioid craving. Novel pharmacotherapies and scalable adjunctive interventions targeting sleep and pain impact should be tested in future work to improve OUD treatment outcomes.

Keyphrases

chronic pain
pain management
physical activity
neuropathic pain
sleep quality
spinal cord
depressive symptoms
cancer therapy
combination therapy