Gad67 haploinsufficiency reduces amyloid pathology and rescues olfactory memory deficits in a mouse model of Alzheimer's disease.

Yue WangZheng WuYu-Ting BaiGang-Yi WuGong Chen

Published in: Molecular neurodegeneration (2017)

Our results demonstrate that GAD67 plays an important role in AD pathology, suggesting that GAD67 may be a potential drug target for modulating the progress of AD.

Keyphrases

mouse model
cognitive decline
working memory
signaling pathway
human health
mild cognitive impairment
adverse drug