Login / Signup

Gonadotroph tumours with a low SF-1 labelling index are more likely to recur and are associated with enrichment of the PI3K-AKT pathway.

Richard A HickmanJeffrey N BruceMarc OttenAlexander G KhandjiXena E FlowersMarkus SiegelinBeatriz LopesPhyllis L FaustPamela U Freda
Published in: Neuropathology and applied neurobiology (2020)
We speculate that patchy SF-1 labelling in GT reflects intratumoural heterogeneity and are less differentiated tumours than diffusely staining GT. SF-1 immunolabelling patterns may have prognostic significance in GT, but confirmatory studies are needed for further validation.
Keyphrases
  • single cell
  • case control
  • flow cytometry