SBSN drives bladder cancer metastasis via EGFR/SRC/STAT3 signalling.

Zhongqiu ZhouZhuojun ZhangHan ChenWenhao BaoXiangqin KuangPing ZhouZhiqing GaoDifeng LiXiaoyi XieChunxiao YangXuhong ChenJinyuan PanRuiming TangZhengfu FengLihuan ZhouLan WangJianan Yang Lili Jiang

Published in: British journal of cancer (2022)

Our findings highlight that SBSN, and secreted SBSN, promote bladder cancer metastasis through activation of EGFR/SRC/STAT3 pathway and identify SBSN as a potential diagnostic and therapeutic target for bladder cancer.

Keyphrases

tyrosine kinase
epidermal growth factor receptor
small cell lung cancer
cell proliferation
muscle invasive bladder cancer
risk assessment
human health
climate change