Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study.

Rebecca C Richmond Nicholas John TimpsonJanine F FelixTom M PalmerRomy GaillardGeorge McMahonGeorge Davey Smith Vincent W V Jaddoe Deborah A Lawlor

Published in: PLoS medicine (2017)

Our findings provide little evidence to support a strong causal intrauterine effect of incrementally greater maternal BMI resulting in greater offspring adiposity.

Keyphrases

weight gain
birth weight
insulin resistance
pregnancy outcomes
high fat diet
body mass index
adipose tissue
preterm birth
current status
type diabetes
metabolic syndrome
physical activity
gestational age
weight loss