Glycomics reveal that ST6GAL1-mediated sialylation regulates uterine lumen closure during implantation.
Kun HanFeiyu WangYulu YueXihong TanMiao TianYiliang MiaoShuhong ZhaoWeijie DongMei YuPublished in: Cell proliferation (2021)
The study reveals a mechanism of uterine lumen closure by identifying that ST6GAL1-mediated α2,6-sialylation of cell adhesion molecules contributes to endometrial fold extension through regulating collective migration of uterine LE.