Optogenetic stimulation of the motor cortex alleviates neuropathic pain in rats of infraorbital nerve injury with/without CGRP knock-down.
Jaisan IslamElina KcByeong Ho OhSoochong KimSang-Hwan HyunYoung Seok ParkPublished in: The journal of headache and pain (2020)
Our findings suggest that optical motor cortex stimulation can alleviate pain behaviors in a rat model of trigeminal neuropathic pain. Transmission of trigeminal pain signals can be modulated via knock-down of α-CGRP and optical motor cortex stimulation.