Circulating VEGF-A, TNF-α, CCL2, IL-6, and IFN-γ as biomarkers of cancer in cancer-associated anti-TIF1-γ antibody-positive dermatomyositis.
Xiaomeng LiYuan HuangYongmei LiuSongxin YanLiubing LiLinlin ChengHaolong LiHaoting ZhanFengchun ZhangYongzhe LiPublished in: Clinical rheumatology (2022)
The present study identified VEGF-A, TNF-α, CCL2, IL-6, and IFN-γ as significant potential biomarkers indicating the presence of cancer and demonstrated a more detailed cytokine profile during diagnosis. These biomarkers could provide better screening strategies and insight into the Cancer TIF1-γ-DM pathogenesis. Key Points • VEGF-A, TNF-α, CCL2, IL-6, and IFN-γ are potential biomarkers of cancer in cancer-associated anti-TIF1-γ antibody-positive dermatomyositis. Potential pathogenic molecular mechanism of the cancer-associated anti-TIF1-γ antibody-positive dermatomyositis.
Keyphrases
- papillary thyroid
- squamous cell
- rheumatoid arthritis
- endothelial cells
- immune response
- interstitial lung disease
- dendritic cells
- disease activity
- lymph node metastasis
- squamous cell carcinoma
- liver injury
- type diabetes
- metabolic syndrome
- skeletal muscle
- adipose tissue
- young adults
- systemic lupus erythematosus
- insulin resistance