Altered irisin/BDNF axis parallels excessive daytime sleepiness in obstructive sleep apnea patients.

Csaba E MoreCsaba PappSzilvia HarsanyiRudolf GesztelyiAngela MikaczoGabor TajtiLaszlo KardosIldiko SeresHajnalka LorinczKrisztina CsapoJudit Zsuga

Published in: Respiratory research (2019)

These results suggest that the irisin-BDNF axis influences subjective daytime sleepiness in OSAS patients reflected by the ESS. These results further imply the possible disruption of the circadian regulation in OSAHS. Future interventional studies are needed to confirm this observation.

Keyphrases

obstructive sleep apnea
end stage renal disease
sleep quality
ejection fraction
newly diagnosed
positive airway pressure
chronic kidney disease
peritoneal dialysis
prognostic factors
sleep apnea
physical activity
stress induced
weight gain