Whole-genome transcriptome and DNA methylation dynamics of pre-implantation embryos reveal progression of embryonic genome activation in buffaloes.

Penghui FuDu ZhangChunyan YangXiang YuanXier LuoHaiying ZhengYanfei DengQingyou LiuKuiqing CuiFei GaoDeshun Shi

Published in: Journal of animal science and biotechnology (2023)

Our study provides a landscape of transcription and DNA methylation in buffalo PED and reveals deeply the molecular mechanism of the buffalo EGA and genetic programming during buffalo MZT. It will lay a foundation for improving the in vitro development of buffalo embryos.

Keyphrases

genome wide
dna methylation
gene expression
single cell
copy number
rna seq
transcription factor