Shorter periconception maternal telomere length and the risk of congenital cardiac outflow defects in the offspring.
Damiat Aoulad FaresRosalieke E WiegelAlex J EgginkSten P WillemsenJoyce B J van MeursRégine Patricia Maria Steegers-TheunissenPublished in: European journal of clinical investigation (2022)
Shorter maternal relative TL is associated with an approximately 1.3-OR for the risk, per SD in relative TL shortening, of VSD in the offspring. These findings need further confirmation in other studies on the predictive value of maternal TL.