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Synthesis and crystallographic characterization of 6-hydroxy-1,2-dihydropyridin-2-one.

Sara K PhillipsSavannah G BrancatoSamantha N MacMillanMark J SniderAndrew J RoeringKatherine A Hicks
Published in: Acta crystallographica. Section E, Crystallographic communications (2023)
The title compound, C 5 H 5 NO 2 , is a hy-droxy-lated pyridine ring that has been studied for its involvement in microbial degradation of nicotinic acid. Here we describe its synthesis as a formic acid salt, rather than the standard hydro-chloride salt that is commercially available, and its spectroscopic and crystallographic characterization.
Keyphrases
  • molecular docking
  • microbial community
  • molecular dynamics simulations