Sec61γ is a vital protein in the endoplasmic reticulum membrane promoting tumor metastasis and invasion in lung adenocarcinoma.

Shanqi XuXin LiJianxiong GengYingyue CaoYan Yu Lishuang Qi

Published in: British journal of cancer (2023)

Sec61γ promoted the proliferation, metastasis, and invasion of LUAD through EGFR pathways. Sec61γ might be a potential target for the treatment of LUAD metastases.

Keyphrases

endoplasmic reticulum
cell migration
small cell lung cancer
epidermal growth factor receptor
signaling pathway
tyrosine kinase
amino acid