Multinuclear Residual Quadrupolar Couplings for Structure and Assignment.
Michael JohnFranziska RüttgerPublished in: Chemphyschem : a European journal of chemical physics and physical chemistry (2024)
Most stable isotopes have a nuclear spin >1/2, but the quadrupole interaction poses challenge on their detection by nuclear magnetic resonance (NMR). On the other hand, the quadrupole interaction is a rich source of structural information that may be exploited for solution NMR in the form of residual quadrupolar couplings (RQCs) of weakly oriented samples. While 2 H RQCs are now well established for structure verification and enantiomeric discrimination of organic molecules, we will in this article highlight some recent work on RQCs of other nuclei (especially 7 Li and 11 B).
Keyphrases
- magnetic resonance
- solid state
- mass spectrometry
- liquid chromatography
- tandem mass spectrometry
- high performance liquid chromatography
- high resolution
- gas chromatography
- simultaneous determination
- contrast enhanced
- capillary electrophoresis
- room temperature
- single molecule
- loop mediated isothermal amplification
- label free
- healthcare
- density functional theory
- real time pcr
- solid phase extraction
- water soluble
- transition metal
- social media