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Comprehensive proteomics investigation of P. vivax-infected human plasma and parasite isolates.

Apoorva VenkateshShalini AggarwalSwati KumarSrushti RajyaguruVipin KumarSheetal BankarJayanthi ShastriSwati PatankarSanjeeva Srivastava
Published in: BMC infectious diseases (2020)
A parasite proteomics investigation is essential to understand disease pathobiology and design novel interventions. Control strategies against P. vivax also depend on early diagnosis. This work provides deeper insights into the biology of P. vivax by identifying proteins expressed by the parasite during its complex life-cycle within the human host. The study also reports antigens that may be explored as diagnostic candidates.
Keyphrases
  • plasmodium falciparum
  • life cycle
  • mass spectrometry
  • endothelial cells
  • label free
  • physical activity
  • dendritic cells
  • toxoplasma gondii
  • induced pluripotent stem cells
  • trypanosoma cruzi
  • genetic diversity