CCAAT/Enhancer-Binding Protein β Mediates Oxygen-Induced Retinal Neovascularization via Retinal Vascular Damage and Vascular Endothelial Growth Factor.

Tingting LiXuan CaiXiang-Ning WangXueyan ZhangHui ZhangBiwei XuShiwei LiJianyan Hu Qiang Wu

Published in: Journal of diabetes research (2020)

C/EBP β shRNA inhibits RNV in OIR. A potential mechanism may be that the activity of C/EBP β increases with its overexpression, which in turn aggravates the amount of the retinal vascular damage and promotes transcription of VEGF. C/EBP β might be a new therapeutic target for preventing RNV.β (C/EBP β (C/EBP β (C/EBP.

Keyphrases

vascular endothelial growth factor
diabetic retinopathy
optical coherence tomography
binding protein
transcription factor
endothelial cells
oxidative stress
optic nerve
diabetic rats
risk assessment
climate change
quantum dots