Cerebral blood flow and cerebrovascular reactivity correlate with severity of motor symptoms in Parkinson's disease.
Laura PelizzariMaria Marcella LaganàFederica RossettoNiels BergslandMirco GalliGiuseppe BaselliMario ClericiRaffaello NemniFrancesca BaglioPublished in: Therapeutic advances in neurological disorders (2019)
CBF and CVR assessment provides information about NVU integrity in an indirect and noninvasive way. Our findings support the hypothesis of NVU involvement at the mild to moderate stages of PD, suggesting that CBF and CVR within the motor network might be used as either diagnostic or prognostic markers for PD.