Effects of Neoadjuvant Chemotherapy Toxicity and Postoperative Complications on Short-term and Long-term Outcomes After Curative Resection of Gastric Cancer.
Chaorui WuNianchang WangHong ZhouTongbo WangQikun MaoXiaojie ZhangDongbing ZhaoPublished in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2019)
The administration of NAC is not associated with an elevated risk of POCs. For patients treated with NAC, NCT is an independent predictor of POCs, but does not affect oncologic outcomes. POCs is independently associated with worse DFS but not OS. NAC should be considered a safe approach in patients who have locally advanced GC. Strategies to minimize chemotherapy toxicity and postoperative morbidities associated with NAC are warranted.
Keyphrases
- locally advanced
- neoadjuvant chemotherapy
- rectal cancer
- transcription factor
- squamous cell carcinoma
- end stage renal disease
- phase ii study
- sentinel lymph node
- chronic kidney disease
- prognostic factors
- lymph node
- genome wide analysis
- newly diagnosed
- oxidative stress
- peritoneal dialysis
- patients undergoing
- adipose tissue
- type diabetes
- high resolution
- radical prostatectomy
- gas chromatography
- weight loss