TNF-alpha inhibitor adalimumab attenuates endotoxin induced cardiac damage in rats.

Selim Durmaz Tünay Kurtoğlu Emin Barbarus Nuket Özkavruk Eliyatkın Mustafa Yılmaz

Published in: Acta cirurgica brasileira (2020)

Adalimumab pretreatment reduces endotoxin-induced myocardial damage in rats. This beneficial effect is thought to be related to the reduction of cytokine release.

Keyphrases

rheumatoid arthritis
high glucose
diabetic rats
oxidative stress
drug induced
heart failure
ulcerative colitis
systemic lupus erythematosus