Immunosuppressant quantification in intravenous microdialysate - towards novel quasi-continuous therapeutic drug monitoring in transplanted patients.

Susanne WeberSara TombelliAmbra GiannettiCosimo TronoMark O'ConnellMing WenAna B DescalzoHeike BittersohlAndreas BietenbeckPierre MarquetLutz RendersGuillermo OrellanaFrancesco BaldiniPeter B Luppa

Published in: Clinical chemistry and laboratory medicine (2020)

The new microdialysis-supported immunosensor allows real-time analysis of immunosuppressants and tailor-made dosing according to the AUC concept. It readily lends itself to future applications as minimally invasive and continuous near-patient TDM.

Keyphrases

minimally invasive
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis