Prevalence, characteristics, management, and outcomes of difficult-to-treat inflammatory bowel disease.

Tommaso Lorenzo ParigiLuca MassiminoAlfredo CariniRoberto GabbiadiniPeter BertoliMariangela AlloccaCristina BezzioArianna Dal BuonoFerdinando D'AmicoFederica FurfaroLaura LoyAlessandra ZilliFederica UngaroVipul JairathLaurent Peyrin-BirouletAlessandro ArmuzziSilvio Danese

Published in: Journal of Crohn's & colitis (2024)

DTT-IBD was prevalent in approximately one-quarter of patients with IBD in a tertiary care setting. Certain IBD phenotypes and the delay in initiating treatment in CD were risk factors for DTT. Drug persistency decreased progressively with every subsequent line of therapy.

Keyphrases

tertiary care
ulcerative colitis
risk factors
emergency department
stem cells
metabolic syndrome
adipose tissue
combination therapy
insulin resistance