Prediction of solution properties and dynamics of RNAs by means of Brownian dynamics simulation of coarse-grained models: Ribosomal 5S RNA and phenylalanine transfer RNA.

Aarón Ayllón BenítezJosé Ginés Hernández CifreFrancisco Guillermo Díaz BañosJosé García de la Torre

Published in: BMC biophysics (2015)

The general good agreement between our results and some experimental data indicates that the model is able to capture the tertiary structure of RNA in solution. Our simulation results also compare quite well with other numerical data. An advantage of the scheme described here is the possibility of visualizing the real time macromolecular dynamics.

Keyphrases

molecular dynamics
electronic health record
nucleic acid
molecular dynamics simulations
virtual reality
machine learning
data analysis
solid state
fluorescent probe