Distinct migratory pattern of naive and effector T cells through the blood-CSF barrier following Echovirus 30 infection.

Marie WiatrCarolin Stump-GuthierDaniela LatorreStefanie UhligChristel WeissJorma IlonenBritta EngelhardtHiroshi IshikawaChristian SchwerkHorst SchrotenTobias TenenbaumHenriette Rudolph

Published in: Journal of neuroinflammation (2019)

Taken together these results suggest that naive CD8+ and Th1 effector cells are highly efficient to migrate through the BCSFB in an inflammatory environment. The T cell phenotype is modified during the migration process through HIBCPP cells.

Keyphrases

highly efficient
induced apoptosis
cell cycle arrest
hiv infected
oxidative stress
regulatory t cells
endoplasmic reticulum stress
cell death
cell proliferation
type iii