Newer-generation antihistamines and the risk of adverse events in children: A systematic review.
Michael MiligkosMaria DakoutrouEleni StathaNikoletta A TheochariIlektra Antonia MavroeidiΙoanna PankozidouIrene PapaconstadopoulosNikolaos G PapadopoulosPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2021)
Our findings confirm that newer-generation AHs have a favorable safety and tolerability profile. However, we could not draw firm conclusions regarding the comparative safety profile of the newer-generation AHs due to the paucity of head-to-head RCTs, variation in definitions and reporting of AEs, and short follow-up duration.