IL-17 Affects the Progression, Metastasis, and Recurrence of Laryngeal Cancer via the Inhibition of Apoptosis through Activation of the PI3K/AKT/FAS/FASL Pathways.

Yang Song Ming Yang Hongjian Zhang Yan Sun Ye Tao Huihui Li Jing Zhang Yuncheng Li Jianming Yang

Published in: Journal of immunology research (2020)

In summary, these findings demonstrated for the first time the role of IL-17 as a tumor promoter and a prometastatic factor in LC and indicated that IL-17 may have an oncogenic role and serve as a potential prognostic biomarker and therapeutic target in LC.

Keyphrases

transcription factor
oxidative stress
dna methylation
gene expression
mass spectrometry
papillary thyroid
cell death
squamous cell
cell cycle arrest
liquid chromatography
risk assessment
signaling pathway
lymph node metastasis
high resolution
high resolution mass spectrometry
childhood cancer