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Synchronous primary cutaneous melanomas: a descriptive study of their clinical features, histology, genetic background of the patients and clinical outcomes.

A Antúnez-LaySebastian PodlipnikCristina CarreraMiriam PotronyG Tell-MartíC BadenasJ A Puig-ButilleN EspinosaSusana Puig SardàJ Malvehy
Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2022)
Synchronous melanomas are more frequent than previously reported and are more frequent in older patients compared to single melanomas. Moreover, these patients have a higher risk of developing a new primary melanoma during follow-up and have higher rates of germline susceptibility variants. Nevertheless, these findings were not associated with worse outcomes.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • chronic kidney disease
  • prognostic factors
  • gene expression
  • adipose tissue
  • copy number
  • genome wide
  • oxidative stress
  • dna methylation
  • dna damage
  • dna repair
  • glycemic control