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Oxytocin Receptors on Calvarial Periosteal Innervation: Therapeutic Target for Post-Traumatic Headache?

Vimala N BharadwajMichael KlukinovRobert Paul CowanNazanin MahinparvarDavid John ClarkDavid Clifford Yeomans
Published in: Pharmaceutics (2024)
Taken together, our observations suggest that periosteal trigeminal afferents contribute to post-TBI craniofacial pain, and that periosteum tissue can be used as a potential local target for therapeutics such as oxytocin.
Keyphrases
  • neuropathic pain
  • traumatic brain injury
  • chronic pain
  • pain management
  • small molecule
  • spinal cord
  • severe traumatic brain injury
  • spinal cord injury
  • bone regeneration
  • human health
  • risk assessment
  • climate change