Differed IL-1 Beta Response between Active TB and LTBI Cases by Ex Vivo Stimulation of Human Monocyte-Derived Macrophage with TB-Specific Antigen.
Meng-Rui LeeLih-Yu ChangChia-Hao ChangBo-Shiun YanMing-Chia LeeWan-Hsin LinPublished in: Disease markers (2019)
This study revealed that macrophage-specific IL-1b response differed among different stages of Mycobacterium tuberculosis infection. The role of IL-1b and inflammasome in the process of LTBI progressing to active TB warrants further investigation.