Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies.

Nur Aizati Athirah DaudJorieke E H BergmanMonika P OktoraWilhelmina S Kerstjens-FrederikseHenk GroenJens H BosEelko HakBob Wilffert

Published in: PloS one (2017)

Some of the drugs which are substrates or inhibitors of placental transporters were commonly used during pregnancy. No significant effect of transporter inhibition was found on fetal drug exposure, possibly due to a limited number of exposures.

Keyphrases

drug induced
air pollution
adverse drug
birth weight
physical activity
pregnant women
body mass index
pregnancy outcomes
weight loss
preterm birth
electronic health record