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Maternal varicella antibodies in children aged less than one year: Assessment of antibody decay.

Shelly BolotinStephanie L HughesRachel D SavageElizabeth McLachlanAlberto SeveriniCallum ArnoldSusan E RichardsonNatasha S CrowcroftShelley DeekScott A HalperinKevin A BrownTodd F HatchetteSelma OsmanJonathan B GubbayMichelle Science
Published in: PloS one (2023)
We found that varicella maternal antibody levels wane rapidly in infants, leaving most infants susceptible by four months of age. Our findings have implications for the timing of first dose of varicella-containing vaccine, infection control measures, and infant post-exposure prophylaxis recommendations.
Keyphrases
  • birth weight
  • pregnancy outcomes
  • clinical practice
  • pregnant women