FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM2.

Jianhua RaoHao WangMing NiZeng WangZiyi WangSong WeiMu LiuPeng WangJiannan QiuLei ZhangChen WuHongbing ShenXue-Hao WangFeng ChengLing Lu

Published in: Gut (2022)

Macrophage FSTL1 promotes the progression of liver fibrosis by inducing M1 polarisation and inflammation based on the intracellular PKM2 reprogramming function of macrophages.

Keyphrases

liver fibrosis
adipose tissue
oxidative stress
reactive oxygen species