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Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment.

Dongki YangJaehong Kim
Published in: Cells (2019)
This review explores the molecular mechanisms that may be responsible for mitochondrial retrograde signalling related metabolic reprogramming in cancer and host cells in the tumour microenvironment and provides a summary of recent updates with regard to the functional modulation of diverse cells in the tumour microenvironment.
Keyphrases
  • induced apoptosis
  • stem cells
  • cell cycle arrest
  • oxidative stress
  • endoplasmic reticulum stress
  • cell death
  • squamous cell carcinoma
  • signaling pathway
  • cell proliferation
  • young adults