Surfactant therapy in late preterm and term neonates with respiratory distress syndrome: a systematic review and meta-analysis.
Viraraghavan Vadakkencherry RamaswamyThangaraj AbiramalathaTapas BandyopadhyayElaine M BoyleCharles Christoph RoehrPublished in: Archives of disease in childhood. Fetal and neonatal edition (2021)
Current evidence base on surfactant therapy in LPT and term infants with RDS indicates a potentially decreased risk of mortality, air leak, PPHN and duration of respiratory support. In view of the low to very low CoE and widely varying thresholds for deciding on surfactant replacement in the included studies, further trials are needed.