Locoregional Failure During and After Short-course Radiotherapy followed by Chemotherapy and Surgery Compared to Long-course Chemoradiotherapy and Surgery - A Five-year Follow-up of the RAPIDO Trial.
Esmée A DijkstraPer J NilssonGeke A P HospersRenu R BahadoerElma Meershoek-Klein KranenbargAnnet G H RoodvoetsHein PutterÅke BerglundAndrés CervantesRogier M P H CrollaMarieke H J van den Beuken-van EverdingenJaume CapdevilaIbrahim EdhemovicCorrie A M MarijnenCornelis J H van de VeldeBengt GlimeliusBoudewijn van Ettennull nullPublished in: Annals of surgery (2023)
The EXP treatment was associated with an increased risk of LRR whereas the reduction in disease-related treatment failure and distant metastases remained after 5 years. Further refinement of the TNT in rectal cancer is mandated.