Biomarkers for the diagnosis of venous thromboembolism: D-dimer, thrombin generation, procoagulant phospholipid and soluble P-selectin.
Nicoletta RivaKevin VellaKieron HickeyLorenza BertùDaniel ZammitSilvana SpiteriSteve KitchenMichael MakrisWalter AgenoAlex GattPublished in: Journal of clinical pathology (2018)
Our results confirmed D-dimer as the main biomarker of VTE and speculated a role for sP-selectin. The impact of thrombin generation was limited and no role emerged for the PPL clotting time. These observations need to be confirmed in large management studies.