The Effects of Topiroxostat, a Selective Xanthine Oxidoreductase Inhibitor, on Arterial Stiffness in Hyperuricemic Patients with Liver Dysfunction: A Sub-Analysis of the BEYOND-UA Study.
Yuya FujishimaHitoshi NishizawaYusuke KawachiTakashi NakamuraSeigo AkariYoshiyuki OnoShiro FukudaShunbun KitaNorikazu MaedaSatoshi HoshideIichiro ShimomuraKazuomi KarioPublished in: Biomedicines (2023)
Topiroxostat improved arterial stiffness parameters in hyperuricemic patients with liver dysfunction, which might be related to its inhibitory effect on plasma XOR.