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Application of Second-Generation Sequencing Technology in Lower Respiratory Tract Infection.

Chong WangShuo YangQi LiuHongchao LiuShangjia JinJiajia ZhengXiumei XiaoXin HouJing LiSisi MaLiyan Cui
Published in: Journal of clinical laboratory analysis (2024)
Different studies discussed the application of second-generation sequencing technology in LRTI from different angles, including the detection of pathogens of LRTI by mNGS and ddPCR, the prediction ability of drug-resistant bacteria, and comparison with traditional methods. We try to analyse the advantages and disadvantages of the second-generation sequencing technology by combing the research results of mNGS and ddPCR. In addition, the development direction of the second-generation sequencing technology is prospected.
Keyphrases
  • drug resistant
  • single cell
  • respiratory tract
  • multidrug resistant
  • acinetobacter baumannii
  • cystic fibrosis
  • case control
  • clinical evaluation